Background & Aims

Dispositional variables such as impulsiveness are related to opioid misuse in people with chronic noncancer pain (CNCP), pain interference is also related to misuse of prescribed medication. Also, Psychological flexibility and inflexibility constitute protective and risk factors of opioid misuse, respectively. Although the empirical literature indicates that these variables are related to opioid misuse, more studies are needed to examine their combined role. This study is aimed at preliminary analysing the relationship between these variables and prescription opioid misuse in a sample of people with CNCP as a part of a more extensive study registered at Open Science Framework.

Methods

The sample was comprised of 66 people with CNCP (29 men and 37 women). Correlations and stepwise regression were used to explore the role of the variables included in the hypothetical model.

Results

Moderate to strong correlations between most of the variables included and opioid misuse were found, except for pain intensity. Stepwise regression analyses showed that pain interference (? = .317, p < .001), psychological inflexibility (? = .256, p < .05) and impulsiveness (? = .284, p < .05) explained a 31.5% of the variance of opioid misuse.

Conclusions

Despite these are preliminary analyses, and the sample size was reduced, these results highlight the importance of considering dispositional, psychological and pain related measures prior to the prescription of opioid medication. Moreover, designing psychological interventions focused on impulsiveness and psychological inflexibility may be useful to reduce the risk of prescribed opioid medication misuse.

References

Barrado-Moreno, V., Ramírez-Maestre, C., Esteve, R., & Martínez, A. E. L. (2023, November 23). THE ROLE OF IMPULSIVENESS AND PSYCHOLOGICAL FLEXIBILITY/INFLEXIBILITY ON PAIN INTERFERENCE AND OPIOID MISUSE IN CHRONIC NONCANCER PAIN PATIENTS. https://doi.org/10.17605/OSF.IO/B98ZE.

Barrado-Moreno, V.; Ramírez-Maestre, C; Esteve, R; de la Vega, R.; Serrano-Ibáñez, ER.; Ruiz-Párraga, GT; Sainero-Tirado, G.; Fernández-Baena, M.; Jensen, MP, & López-Martínez, AE. Impulsivity, and Anxiety Sensitivity as Trans-Diagnostic Factors that Explain Individual Differences in Adjustment to Chronic Pain and Opioid Misuse. 13th Congress of the European Pain Federation EFIC©. Budapest (Hungary).

Chou, R., Fanciullo, G. J., Fine, P. G., Miaskowski, C., Passik, S. D., y Portenoy, R. K. (2009). Opioids for chronic noncancer pain: prediction and identification of aberrant drug-related behaviors: a review of the evidence for an American Pain Society and American Academy of Pain Medicine clinical practice guideline. The Journal of Pain, 10(2), 131-146.

Esteve, R., López-Martínez, A. E., Ruíz-Párraga, G. T., Serrano-Ibáñez, E. R. y Ramírez-Maestre, C. (2020). Pain acceptance and pain-related disability predict healthcare utilization and medication intake in patients with non-specific chronic spinal pain. International Journal of Environmental Research and Public Health, 17(15), 5556.

Esteve, R., Marcos, E., Reyes-Pérez, Á., López-Martínez, A. E. y Ramírez-Maestre, C. (2021). Pain acceptance creates an emotional context that protects against the misuse of prescription opioids: a study in a sample of patients with chronic noncancer pain. International journal of Environmental Research and Public Health, 18(6), 3054.

Lin, L. A., Bohnert, A. S., Price, A. M., Jannausch, M., Bonar, E. E. y Ilgen, M. A. (2015). Pain acceptance and opiate use disorders in addiction treatment patients with comorbid pain. Drug and Alcohol Dependence, 157, 136-142.

Rhodes, A., Marks, D., Block-Lerner, J. y Lomauro, T. (2021). Psychological flexibility, pain characteristics and risk of opioid misuse in noncancerous chronic pain patients. Journal of Clinical Psychology in Medical Settings, 28(2), 405-417.

Presenting Author

Victoria Barrado-Moreno

Poster Authors

Victoria Barrado-Moreno

MSc

University of Malaga

Lead Author

E-mail

Rosa Esteve. PhD

University of Málaga

Lead Author

E-mail

Elena R. Serrano-Ibáñez

Universidad de Málaga

Lead Author

E-mail

Andrea Gutiérrez-Extremera

MSc

Universidad de Málaga. Spain

Lead Author

E-mail

Julia Molina

MD

Centro de Salud Cruz de Humilladero, Málaga, Spain

Lead Author

E-mail

Ana B. Domínguez-Márquez

MD

Centro de Salud Cruz de Humilladero, Málaga, Spain

Lead Author

E-mail

Manuel Durán-Giménez

MD

Centro de Salud Cruz de Humilladero, Málaga, Spain

Lead Author

E-mail

Carmen Ramírez-Maestre

PhD

Universidad de Málaga, IBIMA Plataforma BIONAND, Malaga, Spain

Lead Author

E-mail

Topics

  • Other