Background & Aims

Introduction: International scientific collaboration has made it possible to change the course of HIV disease; from fatal to chronic. This provides us a new focus; the quality of those years of life gained. The presence of chronic pain secondary to the disease itself, some of the therapies or associated comorbidities is described but, Is chronic non-cancer pain more prevalent in people living with HIV? There are no studies on this. Objective: To determine the prevalence of chronic non-cancer pain in people living with human immunodeficiency virus (HIV) disease.

Methods

Cross-sectional study carried out at the Arriarán Foundation, a main center that controls the largest number of people living with HIV disease in Chile, between January 2021 and December 2022. Through a self-applied survey, patients who identified having chronic pain were asked to answer the chronic pain grading questionnaires (CGDC), pain DETECT and PHQ 9, validated scales in Chile.

Results

343 patients with a mean age of 42.3 years (92.7% men, 64.1% without comorbidities) were included. 39% of the patients presented chronic pain and 19% acute pain. Of the group with chronic pain, the complementary surveys showed that the highest percentage feels high intensity pain with low associated disability, focused on one painful area, non-neuropathic and with mild or absent depressive symptoms.

Conclusions

There is a higher prevalence of chronic pain in people with HIV disease, when compared with statistics in the uninfected population, behaving similarly in relation to the most frequently affected sites and the percentage of neuropathic pain.

References

1. Comité Consultivo VIH (CCVIH). Sociedad Chilena de Infectología. 40 años de la epidemia del VIH: en el cruce de dos pandemias. Junio 2021.
2. Collins LF, Armstrong WS. What It Means to Age With HIV Infection: Years Gained Are Not Comorbidity Free. JAMA Netw Open. 2020;3(6):e208023. doi:10.1001/jamanetworkopen.2020.8023
3. Hoja informativa — Últimas estadísticas sobre el estado de la epidemia de sida. ONU-SIDA. https://www.unaids.org/es/resources/fact-sheet
4. Guía para el abordaje del VIH y el sida en los medios de comunicación. Red de Comunicadores para el abordaje del VIH y el sida. 2017.
5. Resolución exenta 1111. Aprueba plan nacional para la prevención y control del VIH/SIDA y las ITS, para el periodo 2021-2022. Noviembre 2021.
6. Vigilancia VIH/SIDA. Instituto de Salud Pública. Julio 2022. https://www.ispch.cl/biomedico/vigilancia-de-laboratorio/ambitos-devigilancia/vigilancia-vih-sida/
7. Addis DR, DeBerry JJ, Aggarwal S. Chronic Pain in HIV. Molecular Pain. January 2020. doi:10.1177/1744806920927276
8. Kamerman PR, Moss PJ, Weber J, Wallace VC, Rice AS, Huang W. Pathogenesis of HIV-associated sensory neuropathy: evidence from in vivo and in vitro experimental models. J Peripher Nerv Syst 2012; 17: 19–31.
9. Jiao JM1, Chronic pain disorders in HIV primary care: clinical characteristics and association with healthcare utilization. Pain, 01 Apr 2016, 157(4):931-937.
10. Bilbeny, Norberto. (2019). DOLOR CRÓNICO EN CHILE. Revista Médica Clínica Las Condes. 30. 397-406. 10.1016/j.rmclc.2019.08.002.
11. Dylan R Addis, Chronic Pain in HIV. Mol Pain, Jan-Dec 2020;16
12. https://www.fundacionarriaran.cl/
13. Maldonado P., Miranda A., Rivera C., Validación del cuestionario para graduación de dolor crónico en pacientes chilenos con patología musculoesquelética. Rev El dolor. Num 63. Pag 18-24, Julio 2015.
14. Rainer Freynhagen, Roberto Rey & Charles Argoff (2020) When to consider “mixed pain”? The right questions can make a difference!, Current Medical Research and Opinion,36:12, 2037-2046, DOI: 10.1080/03007995.2020.1832058
15. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16:606-13. 24
16. Ministerio de Salud. Guía clínica AUGE. Síndrome de la Inmunodeficiencia Adquirida VIH/SIDA. Serie Guías Clínicas Minsal 2013.
17. Arriagada L., Carrasco T., Araya M., Polifarmacia y deprescripción en personas mayores, Revista Médica Clínica Las Condes,Volume 31, Issue 2, 2020, Pages 204-210,ISSN 0716-8640, https://doi.org/10.1016/j.rmclc.2020.02.007.
18. Tabach Apraiz A, Lorena Oyanadel M, Gutiérrez Espinoza H, Bueno Buker D. Efectos del tratamiento multimodal en pacientes con síndrome de dolor regional complejo tipo 1 con, al menos, 6 meses de evolución: un estudio descriptivo. Rev Soc Esp Dolor 2019;26(1):6-13.
19. Miaskowski C. Occurrence and characteristics of chronic pain in a communitybased cohortof indigent adults living with HIV infection. J Pain 2011; 12: 10041016.
20. Madden V., Chronic pain in people with HIV: a common comorbidity and threat to quality of life, PainManag.(2020)10(4),253–260
21. Pullen S., Acker C., Kim H., Physical Therapy for Chronic Pain Mitigation and Opioid Use Reduction Among People Living with HIV in Atlanta, GA: A Descriptive Case Series. AIDS Research and Human Retroviruses © Mary Ann Liebert, Inc. DOI: 10.1089/AID.2020.0028
22. Oyanadel L. Presentación Dolor Crónico en establecimientos de alta complejidad UDCNO HCSBA, 02 Marzo 2020.

Presenting Author

Melissa Barraza

Poster Authors

Melissa Barraza

PM&R MD

Hospital del Trabajador, Santiago de Chile

Lead Author

E-mail

Topics

  • Specific Pain Conditions/Pain in Specific Populations: Pain in Infectious Diseases