Background & Aims
To our knowledge, only one clinical trial (FIBROWALK-study) has reported the effect of adding neuroscience education to a multicomponent intervention program for the treatment of patients with FM.(15) Nevertheless, for the treatment of FM, there are no studies including graded motor imagery (GMI) and therapeutic neuroscience education (TNE) into multicomponent intervention program. Thus, this study aimed to assess the short-term effects of a novel multicomponent intervention program combined with GMI and TNE on improving pain intensity, physical function, and other clinical outcomes compared to standard treatment that include pharmacotherapy and physician education in women with FM.
Methods
Design: Randomized controlled trial with concealed allocation, and blinded assessors. Participants: Sixty-five women with a clinical diagnosis of FM were randomly allocated (1:1) into two groups. Interventions: The control group (n=32) received a standard 12-week treatment including pharmacotherapy and standard physician education, and the intervention group (n=33) received a Novel multicomponent treatment combined with graded motor imagery and neuroscience education. Outcomes measures: The primary outcome was the numeric pain rating scale (NPRS). Secondary outcomes were the Fibromyalgia Impact Questionnaire (FIQ), pain catastrophizing scale (PCS), Tampa Scale Kinesiophobia (TSK-17) and Pittsburgh Sleep Quality Index (PSQI). Measures were taken before and after the 12-week intervention period
Results
After the 12-week intervention period, the multicomponent treatment showed a decrease in pain intensity (NPRS) by -1.18 points (eta squared [?²] =0.47, p<0.001). The experimental group was for FIQ was -16.21 (?²=0.58, p<0.001), for total domain in the PCS was -12.5 (?²=0.61, p<0.001), for the TSK-17 was -6.15 (?²=0.52, p<0.001), for the PSQI was -2.74 (?²= 0.54, p<0.001). All differences were in favor of the multicomponent treatment group with a large effect size.
Conclusions
Considering the results of this study, in the short-term, the efficacy of novel multicomponent treatment combined with GMI and TNE provides significant effects in all clinical outcomes compared to standard treatment in women with FM. Our findings must be interpreted in the context of the studied population; however, this research has important clinical implications because demonstrate that novel multicomponent treatment could be a primary intervention and approachable for patients with FM. Further studies are needed to support long-term clinical efficacy in patients with FM.
References
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Presenting Author
Felipe Araya-Quintanilla
Poster Authors
Felipe Araya-Quintanilla, BPT, MsC. PhD
PT, MSc, PhD
Escuela de Kinesiología, Facultad de Odontología y Ciencias de la Rehabilitación, Universidad San Se
Lead Author
Robinson Ramírez-Vélez
PhD
Department of Health Sciences, Public University of Navarra, Navarrabiomed-IdiSNA, Complejo Hospital
Lead Author
Iván Cuyul-Vásquez
PT
Dpto. de Procesos Terapéuticos, Facultad de Cs. de la salud. Universidad Católica de Temuco, Chile
Lead Author
Héctor Gutiérrez-Espinoza
PT
Universidad de las Americas, Quito. Ecuador
Lead Author
Celia Álvarez-Bueno
PhD
Universidad de Castilla - La Mancha, Spain
Lead Author
Topics
- Specific Pain Conditions/Pain in Specific Populations: Fibromyalgia